Product Description
The YR01868 PCR Thermal Cycler from Kalstein is a highly advanced laboratory device designed to provide precise and reliable DNA amplification, essential for a broad range of applications in molecular biology. This model offers a throughput of up to 48 samples simultaneously, optimizing efficiency in high-demand environments.
Equipped with two fluorescence channels, this thermal cycler can execute swift fluorescence scanning in just two seconds. The dye compatibility includes FAM, SYBR Green I, SYTO 9, Eva Green, LC Green in Channel 1, and HEX, VIC, TET, JOE in Channel 2, enhancing versatility in experimental setups.
The YR01868 features a high-brightness LED light source, known for its long life and maintenance-free operation, combined with sensitive photodiodes for detection. The excitation range covers 470nm to 638nm across four channels, while the detection range extends from 525nm to 685nm. This device supports a broad sample dynamic range from 101 to 1010 copies, ensuring adaptability across diverse experiments.
Utilizing Peltier-based heating, this model offers a remarkable heating rate of ≥8.0 ℃/s and a cooling rate of ≥6.2 ℃/s, with exceptional temperature accuracy within ≤0.1 ℃. The thermal gradient ranges from 1℃ to 40 ℃ across eight rows, adaptable for techniques such as thermal gradient PCR, long PCR, and Touch Down PCR. Supported by two control modes—a 7-inch touchscreen and PC direct control—the unit ensures user-friendly operation and robust data management capabilities.
| Model | YR01868 |
| Throughput | 1-48 |
| Fluorescence Channels | 2 |
| Fluorescence Scanning Time | 2s |
| Dye Compatibility | Channel 1: FAM, SYBR Green I, SYTO 9, Eva Green, LC Green |
| Channel 2: HEX, VIC, TET, JOE | |
| Optical System | |
| Light Source | High-brightness, long life and maintenance-free LED light source |
| Detector | Photodiodes (PDs) |
| Excitation Range | CH1: 470nm CH2:523nm CH3:570nm CH4:638nm |
| Detection Range | CH1:525nm CH2:564nm CH3:610nm CH4:685nm |
| Fluorescence Dynamic Range | Adjustable |
| Sample Dynamic Range | From 101 to 1010copies |
| Thermal Black | |
| Heating Method | Peltier |
| Heating Rate | ≥8.0 ℃/s ℃ |
| Cooling Rate | ≥6.2 ℃/s |
| Temperature Accuracy | ≤0.1 ℃ |
| Gradient Range | 1℃-40 ℃ |
| Gradient Block | 8 row |
| Special Temperature Protocol | Thermal gradients PCR, long PCR, Touch Down PCR |
| Sample Testing Linearity and Repeatability | Linear correlation: /r/ ≥ 0.999 |
| Repeatability: cycle threshold (Ct) value CV≤0.5% | |
| Software Functions | |
| Control Modes | Model1: 7 inch touch screen |
| Mode 2: PC direct control | |
| Power Failure Protection | Automatically start running experiments after power supply, no need to wait PC software |
| Data Storage and Transmission | Upload and download through USB disk. 1000 results can be stored in machine |
| Reporting Function | Templates reserved; customized experiment report |
| Key Applications | Relative quantification, absolute quantification, melting curve analysis, SNP analysis |
| Operating System for PC | Win7/Win10/Win11 |
| Power Supply and Power Consumption | AC 100-240V, 50-60HZ; 600VA |
| Weight | 11 Kg (net) |
| Instrument Dimension | 260*400*260mm (W*L*H) |
| Suitable Consumables | 0.2mL clear non-skirt 48-WELL plates, 8-tube strips, single tubes, etc. |
Market Price
The market price for thermal cyclers like the YR01868 varies based on specific configurations and regional factors. Typically, these advanced models can range between $3,000 to $10,000, depending on features and additional specifications. For precise pricing and any applicable discounts, we encourage interested buyers to request a quotation directly through Kalstein’s platform to gain competitive and comprehensive pricing insights.
Frequently Asked Questions
What makes the YR01868 stand out from other thermal cyclers?
With its dual fluorescence channels and rapid scanning time, the YR01868 offers enhanced experimental versatility and speed, making it a standout choice for complex and time-sensitive molecular biology procedures.
Is the device compatible with my current software systems?
The YR01868 supports PC control modes compatible with modern operating systems like Windows 7, 10, and 11, ensuring seamless integration with existing laboratory software environments.
Can I secure the device against power failures?
Yes, the thermal cycler features built-in power failure protection, resuming experiments automatically after power restoration without manual intervention.
Advantages and Disadvantages
Advantages: This model is exceptionally efficient, with a robust heating/cooling system, two fluorescence channels, and dual control modes. It excels in diverse PCR applications due to its high temperature precision and adjustable dynamic ranges.
Disadvantages: While rich in features, it might be complex for beginners to optimize without proper training, and the initial investment can be substantial, though justified by the performance it delivers.
Field Applications
In practical environments, the YR01868 is utilized extensively across research and diagnostics laboratories. It supports various critical analyses, including relative and absolute quantification, melting curve analysis, and SNP analysis. Its adaptability to different dye systems and customizable protocols makes it foundational for innovations in genetics and diagnostics.
The device’s proficiency in handling large sample throughput makes it a reliable asset for labs engaging in high volume experiments, setting a benchmark in terms of accuracy and speed.
Recommendations
To maximize the YR01868’s capabilities, regular firmware updates and calibration checks are recommended. Training operators on advanced features will ensure optimized usage. Proper handling and maintenance, according to the manufacturer’s guidelines, will prolong the device’s life span, minimizing potential disruptions during critical investigations.
For laboratories seeking a comprehensive solution, leveraging Kalstein Plus services allows for streamlined equipment procurement and support, tailored precisely to your operational requirements.
If you are looking for a fusion of innovation and quality, you have come to the right place. At Kalstein, we offer you the luxury of exploring our exclusive catalog of laboratory equipment. We manufacture each piece of equipment with a level of excellence. Our intuitive and agile online purchasing channels are designed for your convenience, ensuring the most friendly prices. Don’t hesitate any longer, we bring science to life, it’s time to be part of our community. https://kalstein.net/en/product/pcr-thermal-cyclers-yr01868/.
