What is the pathological anatomy?

The main objective of pathological anatomy is not only to study the evolution and causes of a disease, but also to make a prognosis of the effects that different diseases can have on human beings. To do this, tumor cells and body tissues are analyzed.

Thus, within pathological and cytodiagnostic studies, two types of tests are differentiated: pathological and diagnostic. In the first of them, a sample of the tissue of any organ is analyzed with the intention of identifying the type of cell and what treatments would be useful to combat the alteration. As for diagnostic tests, they are also known as biopsy and their main objective is to obtain a sample of organic fluid or tissue to study the existence of a disease, with the intention of determining a specific diagnosis.

Among the equipment most used in this science, we have: microtomes, microscopes, tissue processor, water baths for tissues, cryostats, cooling plates, trimmer and paraffin dispenser, slide dryers, tissue inclusion systems, systems of automatic staining for slides, among others.

 
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

Types of products to work in the pathological anatomy sector.

Tissue water bath

It is a fundamental step in every histology laboratory, since it is a fundamental procedure to make courts...

 
 

Tissue Flotation

It is essential that all devices work correctly. This step is very important in all laboratories of histology...

 
 

Cooling plate

The cooling process is a fundamental step in every histology laboratory, since it is a fundamental procedure for...

 
 

Tissue processing

The staining process is a routine technique that reveals exceptional details of the structure of the tissue and the composition of the cells ...

 
 

Slide warmers

In histology laboratories to achieve the correct results. Knowing every detail is one of the qualities you should have...

 
 
 
 

Microtomes series

Microtomy is a method for the preparation of thin sections for materials such as bones, minerals and teeth, and an alternative to electric...

 
 
 
 
 
 
 
 

Automatic Slide Stainer

The staining process is a routine technique that reveals exceptional details of the structure of the tissue and the composition of the cells...

 
 

Paraffin dispenser

Any histology laboratory must have paraffin wax to carry out the processing process so the operator...

 
 

Our best-selling microtome πŸ†

This is a very common type of microtome. It works with a staggered rotary action so that the actual cut is part of the rotary motion. In a rotary microtome, the blade is typically set in a horizontal position. This microtome is the perfect choice for you if you are looking for a standard rotary type.

In the daily routine within a laboratory, microscopic substances and samples are very common. Most of the time it is necessary to cut some of the samples into extremely thin slices of material, known as sections. To prepare a sample and make these types of cuts, it is necessary to have a microtome, a very essential device in the field of microscopy. The use of microtomes allows the preparation of samples for observation under transmitted light or electron radiation.

Microtomy is a method for the preparation of thin sections for materials such as bones, minerals and teeth, and an alternative to electric polishing and ion milling. The microtome sections can be made thin enough to section a human hair across its width. You should know that the model we offer you is a high-end device that will give you the results you need to achieve the exact sample cuts.

Equipment on offer for pathological anatomy practices

At Kalstein we are MANUFACTURERS, so you can BUY everything you need for your pathology laboratory at excellent PRICES. That is why we invite you to take a look at the Products menu.

Rotary microtome YR422

 
 
 
 

Automated slide staining YR436-1

 
 

Tissue Inclusion Center YR439

 
 
 
 

Tissue Inclusion Center YR442

 
 
 
 
 
 
 
 

Cooling plate YR440

Water Bath YR449

Slide Dryer YR453

 
 

Paraffin dispenser YR459

Main equipment used in pathological anatomy

Among the equipment most used in this science, we have: microtomes, microscopes, tissue processor, water baths for tissues, cryostats, cooling plates, trimmer and paraffin dispenser, slide dryers, tissue inclusion systems, systems of automatic staining for slides, among others.

Histopathology

It is the microscopic examination of a sample using histological techniques. Stains provide a specific diagnosis based on morphology and is the core skill of histology.

Electron microscopy

It consists of the examination of tissue with an electron microscope that allows greater magnification, allowing the visualization of organelles within the cell...

Tissue cytogenesis

It is based on the visualization of chromosomes to identify genetic defects such as chromosome translocation...

Immunohistochemistry

It is based on the use of antibodies to detect the presence, abundance and localization of specific proteins. This technique is critical for distinguishing between disorders with...

 
 
Updated Kalstein.

What is your ideal pathological anatomy equipment?

There is an infinity of models, so it is normal that you do not know which team of pathological anatomy purchases to meet your needs. In Kalstein, we evaluate them to find what you are looking for.
 
 
 
 
 
 

What is a microtome for? - Kalstein

Microtomy is the discipline that deals with obtaining fine serial sections from tissues included in paraffin blocks for their subsequent...

 
 
 
 
 
 

What is a cryostat? - Kalstein

The cryostat is a piece of equipment used in the processing of samples for histological or histopathological diagnosis...

 
 
 
 
 
 

Processing for histological studies

Tissue processing is a very important part of any histology laboratory, and begins with obtaining the tissue under study. In the case...

 
 

What types of tests are performed in pathology?

The main objective of pathological anatomy is not only to study the evolution and causes of a disease, but also to make a prognosis of the effects that different diseases can have on human beings. To do this, tumor cells and body tissues are analyzed.

Automatic slide staining YR435-1

Characteristics:

  • Electronic module design. The stainer meets the requirements of conventional staining or special staining. For different laboratories,
    and staining can be accomplished simultaneously or individually for good efficacy.
  • Color touch screen makes entry date and search convenient, different staining schedules, and progress displayed on the interface.
  • Staining program initiated by color code and constantly displayed on the interface.
  • 10 game programs can be processed, the 10-piece staining rack can be processed simultaneously, and any program runs at any time.
  • 26 Reagent Station, two of them can be waiting stations. Optimizes staining progress when multiple staining grids are operating simultaneously.
 
 
 
 
 
 

How to cut bones with a microtome?

The value of the histological examination in the diagnosis and classification of clinical conditions is entrusted to the experience of the pathological anatomy laboratory in handling the wide range of specimen types submitted for analysis.

From receipt of the tissue sample to presentation of the slide for microscopic examination, histologists must consider the composition of the specimen to determine how it should be handled effectively.

Most samples follow a routine cycle of dehydration and wax embedding with paraffin for the purpose of sectioning on the microtome. However, due to its high calcium content, bone is a particularly difficult tissue to section and the density of the sample must be taken into consideration. Cutting decalcified sections of bone requires embedding in a resin, a specialized microtome, and modified staining techniques.

Consequently, most laboratories decalcify bone samples, allowing them to be embedded in paraffin and processed. Nitric acid and formic acid are used as decalcification agents, with formic acid being more suitable for laboratories performing molecular analysis, because unlike nitric acid, it does not destroy DNA.

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What is recommended?

On many occasions, manual sectioning is recommended for paraffin-embedded specimens due to the need to vary the levels of force used to cut various parts of the sample.

Tissues common to analysis, on the other hand, sometimes require larger and thicker sections. As a consequence, these samples sometimes require casting in resin with the use of a fully mechanized microtome that slowly applies force in a constant and controlled manner to thereby generate sections of good quality.

At Kalstein we offer you a wide range of innovative microtomes and pathological anatomy equipment such as specialized bath for histology, paraffin dispensers, cooling plates, tissue processing machines, paraffin inclusion stations. That is why we invite you to take a look at the β€œProducts” menu.

Contact us to know prices and logistics

If you require a quote, you have a question about any product and / or want to clarify any doubt, contact us.

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