In the world of scientific and medical laboratories, thermocyclers are indispensable workhorses. They create controlled temperature fluctuations, necessary for amplifying DNA and other nucleic acids – a crucial step for analyzing biological samples. Among the leading manufacturers, Kalstein stands out, with models that offer a unique blend of precision, speed, and reliability. In this article, we will compare two standout models from this company: the YR01867 and the Mini8 plus.
Comparison of Basic Parameters
The YR01867 is a solidly robust thermocycler, with dimensions of 205mm x 156mm x 153mm and a weight of 3.2Kg. On the other hand, the Mini8 plus is slightly more compact and lighter, with measures of 205mm x 190mm x 98mm, and a weight of 2.1Kg. In terms of consumables, the YR01867 is designed to work with individual 0.2mL clear tubes and 8-strip tubes. Conversely, the Mini8 plus prefers 8X0.2mL PCR tubes.
The advantage of Kalstein here lies in its adaptability to the laboratory’s needs. Their offerings include larger and smaller options, depending on space restrictions and the number of samples that need to be processed. https://kalstein.net/en/product/thermal-cyclers-yr01867/
Comparison of Thermal and Optical Parameters
Both models exhibit Hot-lid working temperature ranges of 40℃-110℃ and control temperature using the Peltier method. However, YR01867 stands out with much higher heating and cooling speeds, boasting an average heating rate of 3.3℃/s against the Mini8 plus’ >1.5°C/s, and an average cooling rate of 3.0℃/s. This model also possesses superior temperature accuracy and uniformity, providing a competitive edge for laboratories seeking precise, consistent results.
The optical parameters of these thermocyclers also have substantial differences. The YR01867 has a detecting wavelength range of 525-685nm and offers compatibility with a diverse array of dye channels. In contrast, the Mini8 plus has fewer fluorescence channels and is only compatible with two types of dyes.
Other Advantages and Disadvantages
The YR01867 offers versatility with three different control modes and a 2-year warranty, while the Mini8 plus has only a one-year warranty and is controlled via Windows. Both models provide Internet, USB, and WiFi connections.
Before deciding on the purchase or sale of a thermocycler, lab-specific requirements must be considered. For laboratories requiring high speed and precision, Kalstein’s YR01867 is a reliable and robust option. However, for labs with limited space or a lower quantity of samples, the Mini8 plus may be a viable option due to its compact size and lower price. In any case, Kalstein stands out as a leading manufacturer with high-quality equipment, offering relevant and durable laboratory solutions.
