Product Description
The YR01869 Thermal Cycler by Kalstein is a cutting-edge laboratory device designed to enhance the precision and efficiency of PCR (Polymerase Chain Reaction) testing. With a remarkable throughput of 1-96, this model allows for high-volume processing, making it ideal for both research and routine diagnostic applications. It is equipped with six fluorescence channels, ensuring versatile dye compatibility and enabling a wide range of test configurations. The fluorescence scanning time stands at an impressive 7 seconds, providing swift results without sacrificing accuracy.
Moreover, the thermal cycler boasts a state-of-the-art optical system featuring a high-brightness, long-life, and maintenance-free LED light source, with excitation from the top. The photodiode detectors ensure precise top scanning, and the adjustable fluorescence dynamic range enhances the sensitivity and specificity of your assays. Its Peltier heating method supports a rapid heating rate of over 6.1 °C/s and a cooling rate of over 5.0 °C/s, maintaining temperature uniformity and accuracy.
| Model | YR01869 |
|---|---|
| Throughput | 1-96 |
| Fluorescence Channels | 6 |
| Fluorescence Scanning Time | 7s |
| Dye Compatibility | Channel 1: FAM, SYBR Green I , SYTO 9, Eva Green, LC Green |
| Channel 2: HEX, VIC, TET, JOE | |
| Channel 3: ROX, Texas Red | |
| Channel 4: Cy5 | |
| Channel 5: Alexa Fluor 680 | |
| Channel 6: FRET | |
| Light Source | High-brightness, long life and maintenance-free LED light source, excitation from the top |
| Detector | Photodiodes (PDs), top scanning |
| Excitation Range | CH1: 465nm CH2:527nm CH3:580nm CH4:632nm CH5:680nm CH6:465nm |
| Detection Range | CH1: 510nm CH2:563nm CH3:616nm CH4:664nm CH5:730nm CH6:616nm |
| Fluorescence Dynamic Range | Adjustable |
| Sample Dynamic Range | From 101 to 1010copies |
| Heating Method | Peltier |
| Heating Rate | >6.1 ℃/s |
| Cooling Rate | >5.0 ℃/s |
| Temperature Uniformity | ±0.1 ℃ |
| Temperature Accuracy | ≤0.1 ℃ |
| Gradient Range | 1℃-40 ℃ |
| Gradient Block | 12 row |
| Special Temperature Protocol | Thermal gradients PCR, long PCR, Touch Down PCR |
| Sample Testing Linearity and Repeatability | Linear correlation: /r/ ≥ 0.999 |
| Repeatability: cycle threshold (Ct) value CV≤0 0.5% | |
| Control Modes | Model 1: 10.4 inch touch screen |
| Mode 2: PC direct control | |
| Power Failure Protection | Automatically start running experiments after power supply, no need to wait PC software |
| Data Storage and Transmission | Upload and download through USB disk. 1000 results can be stored in machine |
| Reporting Function | Templates reserved; customized experiment report |
| Key Applications | Relative quantification, absolute quantification, melting curve analysis ,SNP analysis |
| Operating System for PC | Win7/Win10/Win11 |
| Power Supply and Power Consumption | AC 100-240V,50-60HZ, 900VA |
| Weight | 30 Kg (net) |
| Instrument Dimension | 555*475*484mm (W*L*H) |
| Suitable Consumables | 0.2mL 96-well plates, 8-tube strips, single tubes(clear, frosted and white). |
Market Price
In the dynamic marketplace of laboratory equipment, the cost of thermal cyclers can vary significantly based on features and capabilities. The YR01869 Thermal Cycler by Kalstein, given its advanced technological attributes, generally falls within the price range of $28,000 to $29,500 USD. However, the precise pricing can depend on factors such as geographical location, procurement volumes, and distributor agreements. We encourage potential buyers to request a personalized quote to get accurate pricing information tailored to their needs.
Frequently Asked Questions
What are the compatibility requirements for computer systems?
The YR01869 Thermal Cycler is compatible with modern Windows operating systems, including Win7, Win10, and Win11, ensuring seamless integration with existing lab infrastructure.
Is there any special training required to operate the cycler?
While the thermal cycler is designed for user-friendly operation with a 10.4-inch touch screen and PC direct control, we recommend reviewing the manual and undergoing a brief training session to maximize the device’s functionality and efficiency.
How is data handled and stored?
Data can be uploaded and downloaded via USB, and the device can store up to 1000 results internally, facilitating efficient data management and archiving.
Advantages and Disadvantages
Advantages: The YR01869 Thermal Cycler stands out with its rapid heating and cooling rates, top-notch fluorescence detection capabilities, and flexible dye compatibility. Its robust design ensures durability, while features like power failure protection and customizable reporting functions offer operational reliability and ease of use in lab settings.
Disadvantages: The primary limitation is the initial investment cost, which is relatively high compared to simpler models. However, the added value in terms of precision and versatility can outweigh the financial outlay for labs with demanding throughput needs.
Usage in the Field
The YR01869 Thermal Cycler is employed across diverse research and clinical labs for conducting PCR tests, essential for DNA amplification, gene expression analysis, and genotyping. Its advanced features enable precise thermal cycling protocols, crucial for experiments requiring variable temperature gradients and consistent repeatability across different runs.
In practical use, it facilitates applications such as relative and absolute quantification, melting curve analysis, and SNP analysis, proving indispensable for both research-oriented and diagnostic labs aiming for high-throughput solutions.
Recommendations
To ensure optimal performance from the YR01869, regular calibration checks and software updates are recommended. Utilize compatible consumables, such as 0.2mL 96-well plates, to guarantee accuracy and reliability in results. Additionally, maintaining a clean environment and following manufacturer guidelines can extend device longevity and enhance output quality.
For labs interested in leveraging cutting-edge technology, consider integrating the YR01869 into your workflows for improved efficiency. Request a quote from Kalstein Plus and explore customization options that fit your laboratory’s unique requirements. This investment not only amplifies lab productivity but also ensures your research benefits from the latest technological advancements in thermal cycling.
If you are looking for a fusion of innovation and quality, you have come to the right place. At Kalstein we offer you the luxury of exploring our exclusive catalog of laboratory equipment. We manufacture each piece of equipment with a level of excellence. Our intuitive and agile online shopping channels are designed for your convenience, ensuring the friendliest prices. Do not hesitate any longer, we bring science to life, it’s time to be part of our community. https://kalstein.net/en/product/thermal-cyclers-yr01869/.
